Payer PolicyActive
CMM-204: Prolotherapy
EVICORE-MSK_ADVANCED-C04AAEBA
EviCore by Evernorth
Effective: February 15, 2019
Updated: January 13, 2026
created · Dec 5, 2025
Policy Summary
Prolotherapy (CPT M0076) for musculoskeletal pain or instability (e.g., laxity, weakness) is considered experimental, investigational, or unproven and is not covered. The guideline lists no covered indications and specifies no required documentation or other approval criteria.
Coverage Criteria Preview
Key requirements from the full policy
"Based on the lack of conclusive scientific evidence demonstrating the clinical efficacy of prolotherapy combined with the potential to expose individuals to adverse side effects or complications, t..."
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