Immune Globulin Intravenous (IVIg)

This LCD covers IVIg for specific autoimmune, neurologic, hematologic, transplant-related, and primary immunodeficiency conditions when diagnosis is well-documented and alternative therapies have failed or are contraindicated; certain indications (e.g., dermatomyositis and relapsing-remitting MS) require failure of other therapy. CIDP and variants require specialist consultation and objective, quantitative monitoring (e.g., MRC, ADL) with documented benefit for continuation; IVIg is explicitly not reimbursed for epilepsy, ALS, paraneoplastic syndromes, undiagnosed neuropathy/weakness, or malignancies without neurologic linkage.

"IVIg is covered for pregnant women with idiopathic thrombocytopenic purpura (ITP) who have previously delivered infants with autoimmune thrombocytopenia."

Sign up to see full coverage criteria, indications, and limitations.