LCDActive
MolDX: HLA-DQB1*06:02 Testing for Narcolepsy
L36464
Effective: August 24, 2023
Updated: December 31, 2025
Policy Summary
HLA-DQB1*06:02 typing (CPT 81383) for narcolepsy is considered experimental/investigational/unproven and is not covered for any population. The test is insufficient to confirm or exclude narcolepsy, does not quantify individual risk, and currently provides no clinical utility for diagnosis or management.
Coverage Criteria Preview
Key requirements from the full policy
"HLA-DQB1*06:02 typing (CPT 81383) for the diagnosis or management of narcolepsy is considered experimental, investigational, or unproven for all populations and is therefore not covered."
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