<b> MolDX: HLA-DQB1*06:02 Testing for Narcolepsy</b>

HLA-DQB1*06:02 typing (CPT 81383) for narcolepsy is considered experimental/investigational and is not covered for any population. The test is insufficient to confirm, exclude, or quantify risk of narcolepsy and therefore has no demonstrated clinical utility; diagnosis should rely on clinical evaluation plus PSG, MSLT, and CSF hypocretin-1 testing per ICSD-3/DSM-5.

"HLA-DQB1*06:02 typing (CPT 81383) for the diagnosis or management of narcolepsy is considered experimental, investigational, and unproven and is not covered for all populations."

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