Wound Application of Cellular and/or Tissue Based Products (CTPs), Lower Extremities

Medicare covers CTP application for chronic non-healing lower extremity wounds (primarily diabetic foot ulcers and venous leg ulcers) that have failed appropriate conservative care (generally >4 weeks), provided wounds are partial- or full-thickness with a clean granular base, ≥1.0 cm², free of active infection/osteomyelitis, and have adequate perfusion (e.g., ABI ≥0.60 or toe pressure >30 mmHg). Coverage requires documentation of prior conservative therapy, wound measurements, systemic disease management, and adherence to product labeling; limits include a maximum of 10 applications per wound per 12-week period, typical treatment not to exceed 12 weeks, and exclusion for specific contraindications (uncontrolled systemic disease, active infection, allergy, continued smoking without cessation efforts).

"CTP application is covered for chronic non-healing lower extremity wounds (including diabetic foot ulcers and venous leg ulcers) that have failed to respond to documented appropriate conservative w..."