LCDActive
MolDX: DecisionDx-UM (Uveal Melanoma)
L37033
Effective: June 30, 2022
Updated: December 31, 2025
Policy Summary
DecisionDx-UM is covered only for management of newly diagnosed, confirmed uveal melanoma patients without evidence of metastatic disease to determine metastatic risk and guide surveillance and oncology referral. Coverage is limited to this clinical scenario; the policy does not specify testing frequency, detailed documentation forms, or prior authorization requirements and recommends referral preferably to a melanoma-expert medical oncologist.
Coverage Criteria Preview
Key requirements from the full policy
"DecisionDx-UM (Castle Bioscience) is covered for management of newly diagnosed uveal melanoma to determine metastatic risk and to guide surveillance and referral to medical oncology."
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