LCDActive
Lab: Coenzyme Q10 (CoQ10)
L37068
Effective: February 25, 2021
Updated: December 6, 2025
Policy Summary
Serum or other body‑fluid testing for Coenzyme Q10 (CoQ10) is explicitly non‑covered for all indications by this Noridian LCD (examples: heart disease, statin myopathy, cancer, neurologic disorders, migraine prophylaxis, infertility, etc.). No documentation or other requirements will make testing payable (CoQ10 testing is not a Medicare benefit), the evidence of clinical utility is weak/controversial, and this is a local Noridian MAC determination (not an NCD) with anticipated retirement 10/16/2025.
Coverage Criteria Preview
Key requirements from the full policy
"This is a non-coverage policy for serum or other body fluid testing for levels of Coenzyme Q10 (CoQ10 or Q10), also known as ubiquinone, ubidecarenone, coenzyme Q, for all diseases."
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