LCDActive
MolDX: DecisionDx-UM (Uveal Melanoma)
L37130
Effective: May 22, 2025
Updated: December 31, 2025
Policy Summary
DecisionDx-UM testing is covered for management of newly diagnosed uveal melanoma patients who have a confirmed diagnosis and no evidence of metastatic disease. The test is intended to determine metastatic risk and to guide surveillance and referral to medical oncology (preferably a melanoma specialist). Documentation should demonstrate the diagnosed uveal melanoma, absence of metastasis, and clinical intent to use test results for management decisions.
Coverage Criteria Preview
Key requirements from the full policy
"DecisionDx-UM test (Castle Bioscience) is covered for management of newly diagnosed uveal melanoma."
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