LCDActive
MolDX: Breast Cancer Index® (BCI) Gene Expression Test
L37832
Effective: October 23, 2025
Updated: December 31, 2025
Policy Summary
The BCI gene expression test is covered only for postmenopausal women with invasive ER+ and/or PR+ and HER2- early-stage breast cancer (T1-T3, pN0-pN1, M0) who have no distant metastasis, when results will be used to guide chemotherapy decisions and/or evaluate late recurrence risk and endocrine therapy extension. Coverage is restricted to this population and clinical use; tests for patients who are premenopausal, HER2+, ER/PR-negative, metastatic (M1), or whose clinical documentation does not show intended use to inform treatment are not covered.
Coverage Criteria Preview
Key requirements from the full policy
"Patient is postmenopausal woman."
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