LCDActive
MolDX: Predictive Classifiers for Early Stage Non-Small Cell Lung Cancer
L38327
Effective: July 3, 2025
Updated: December 31, 2025
Policy Summary
Molecular classifier testing for early-stage non-squamous NSCLC (AJCC 8th edition stage I–IIa) is covered when the patient is a candidate for adjuvant platinum-containing chemotherapy, is sufficiently healthy to tolerate chemotherapy, and the test is ordered by the treating clinician (typically a medical oncologist, surgeon, or radiation oncologist) to inform the adjuvant chemotherapy decision. No additional documentation, frequency limits, or explicit exclusions were specified in the provided policy text.
Coverage Criteria Preview
Key requirements from the full policy
"Patient has non-squamous non-small cell lung cancer (NSCLC) corresponding to American Joint Committee on Cancer (AJCC) 8th edition stage I or stage IIa."
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