LCDActive
MolDX: Repeat Germline Testing
L38353
Effective: April 25, 2024
Updated: December 31, 2025
Policy Summary
Medicare coverage excludes duplicate germline DNA/RNA testing for the same genetic content in the same beneficiary. One lifetime unit of service is allowed per specific germline test; panels that include previously tested genes may be covered only if the untested components have documented clinical utility.
Coverage Criteria Preview
Key requirements from the full policy
"Germline DNA or RNA-based testing is reasonable and necessary when it interrogates genetic content that has not been previously tested in the same Medicare beneficiary and the newly interrogated ge..."
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