MolDX: Genetic Testing for Heritable Thoracic Aortic Disease

Heritable thoracic aortic disease genetic testing is covered for germline tests (LDT, FDA-cleared/approved) when the patient has aortic root/ascending aortic dilation, aneurysm, or dissection per guidelines and at least one risk criterion (age <60, syndromic features, or relevant family history). Tests must include guideline-recommended gene content (ClinGen and ACC/AHA), have completed a MolDX Technical Assessment, and the patient must have been offered genetic counseling; single known familial variant testing is allowed when clinically appropriate.

"Genetic testing for heritable thoracic aortic disease is covered when ALL the following are met: the patient has aortic root or ascending aortic dilation, aneurysm, or dissection (per national cons..."

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