Intracellular Micronutrient Analysis

This policy addresses intracellular micronutrient analysis (functional intracellular/essential metabolic testing) and, although it discusses use for screening in otherwise healthy individuals and for diagnostic evaluation in patients with chronic illnesses or nonspecific generalized symptoms, it explicitly considers these tests experimental, investigational, and not covered. Major limitations include absence of demonstrated clinical validity or utility (no comparative accuracy or RCT evidence), the tests being laboratory‑developed and not FDA‑reviewed, CLIA high‑complexity requirements for performing labs, and billing guidance to report individual CPT codes or use unspecified/unlisted codes as appropriate.

"None — Intracellular micronutrient analysis (functional intracellular/essential metabolic analysis) is considered experimental, investigational and/or unproven and not covered."