NCDActive
Anti-Inhibitor Coagulant Complex (AICC)
NCD150
Effective: January 1, 1966
Updated: December 31, 2025
Policy Summary
Medicare covers anti-inhibitor coagulant complex (AICC) for patients with hemophilia A who have documented factor VIII inhibitor antibodies, are experiencing a major bleeding episode, and have failed to respond to other, less expensive therapies. Coverage is limited to these circumstances and is not provided for patients without inhibitor antibodies, for non-major bleeds, or when less costly therapies have not been exhausted or have been effective. Documentation must show the diagnosis, inhibitor status, details of the major bleed, and prior treatment failures.
Coverage Criteria Preview
Key requirements from the full policy
"Patient has hemophilia A with documented factor VIII inhibitor antibodies."
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