NCDActive
Antigens Prepared for Sublingual Administration
NCD155
Effective: November 17, 1996
Updated: December 31, 2025
Policy Summary
For antigens provided on or after November 17, 1996, Medicare covers allergy immunotherapy only when the antigen is administered by injection. Sublingual administration (drops under the tongue) is explicitly not covered because it has not been demonstrated to be safe and effective.
Coverage Criteria Preview
Key requirements from the full policy
"Medicare covers antigens for allergy therapy only when administered by injection for antigens provided to patients on or after 1996-11-17."
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Covered Medical Codes