NCDActive
Lymphocyte Mitogen Response Assays
NCD257
Effective: May 16, 1983
Updated: December 31, 2025
Policy Summary
Lymphocyte mitogen response assays are covered by Medicare when medically necessary to assess lymphocytic function in diagnosed immunodeficiency diseases or to monitor immunotherapy. The test is explicitly not covered for monitoring cancer treatment because that use is considered experimental. The policy does not specify documentation requirements or frequency limits.
Coverage Criteria Preview
Key requirements from the full policy
"Covered when medically necessary to assess lymphocytic function in patients with diagnosed immunodeficiency diseases."
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