Prolotherapy and Platelet Rich Plasma Therapies – Commercial and Individual Exchange Medical Policyopen_in_new

UnitedHealthcare deems prolotherapy and platelet‑rich plasma (PRP) unproven and not medically necessary for any condition or indication. The policy lists CPT/HCPCS codes for reference only (listing does not imply coverage), provides no specific documentation requirements, and cites low‑quality, heterogeneous evidence with guideline recommendations that routine use be restricted to research or special arrangements and, where studied, generally after failure of conservative therapy.

"For diabetic foot ulcers: PRP discussed 'as an adjunct to conventional wound therapy (CWT) to treat adults who have hard-to-heal diabetic foot ulcers (DFUs) that have not responded to prolonged sta..."

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