Billing and Coding: Amniotic and Placental-Derived Product Injections and/or Applications for Musculoskeletal Indications, Non-Wound

The article implements LCD L39118 and states that amniotic- and placental-derived product injections/applications for non‑wound musculoskeletal indications are considered not reasonable and necessary and are therefore non‑covered. Providers must follow the billing/coding instructions in the article, submit appropriate ICD‑10/CPT/HCPCS codes with supporting documentation of medical necessity (or indicate investigational/clinical trial status per payer rules) when filing claims.